Ahmed Nadeem Selected Research

Autistic Disorder (Autism)

5/2022	Dysregulated Nrf2 signaling in response to di(2-ethylhexyl) phthalate in neutrophils of children with autism.
1/2022	CXCR2 antagonist SB332235 mitigates deficits in social behavior and dysregulation of Th1/Th22 and T regulatory cell-related transcription factor signaling in male BTBR T+ Itpr3tf/J mouse model of autism.
1/2022	Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism.
1/2022	Imbalance in pro-inflammatory and anti-inflammatory cytokines milieu in B cells of children with autism.
2/2021	5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism.
2/2021	Aggravation of autism-like behavior in BTBR T+tf/J mice by environmental pollutant, di-(2-ethylhexyl) phthalate: Role of nuclear factor erythroid 2-related factor 2 and oxidative enzymes in innate immune cells and cerebellum.
1/2021	Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells.
12/2020	Ubiquitous plasticizer, Di-(2-ethylhexyl) phthalate enhances existing inflammatory profile in monocytes of children with autism.
12/2020	3-Aminobenzamide alleviates elevated DNA damage and DNA methylation in a BTBR T+Itpr3tf/J mouse model of autism by enhancing repair gene expression.
7/2020	Elevated expression of toll-like receptor 4 is associated with NADPH oxidase-induced oxidative stress in B cells of children with autism.

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Ahmed Nadeem Research Topics

Disease

49	Inflammation (Inflammations) 01/2022 - 12/2006
35	Autistic Disorder (Autism) 05/2022 - 12/2016
20	Asthma (Bronchial Asthma) 10/2019 - 02/2005
10	Psoriasis (Pustulosis Palmaris et Plantaris) 06/2020 - 09/2015
8	Neuroinflammatory Diseases 01/2020 - 12/2016
6	Rheumatoid Arthritis 01/2020 - 10/2016
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 12/2016
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 06/2022 - 06/2021
4	Acute Kidney Injury (Acute Renal Failure) 10/2021 - 05/2018
4	Experimental Arthritis 03/2021 - 12/2019
4	Sepsis (Septicemia) 01/2021 - 02/2012
4	Neoplasms (Cancer) 01/2019 - 08/2005
4	Nervous System Diseases (Neurological Disorders) 01/2019 - 10/2017
3	Autism Spectrum Disorder 01/2022 - 06/2020
3	Arthritis (Polyarthritis) 03/2021 - 10/2016
3	Acute Lung Injury 06/2020 - 06/2017
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2020 - 01/2016
3	Pneumonia (Pneumonitis) 11/2018 - 07/2010
2	Otitis 01/2022 - 01/2017
2	Colitis 01/2022 - 01/2020
2	Demyelinating Diseases (Demyelinating Disease) 01/2022 - 07/2020
2	Autoimmune Diseases (Autoimmune Disease) 07/2020 - 01/2020
2	Carcinogenesis 01/2020 - 01/2019
2	Cardiotoxicity 11/2017 - 12/2014

Drug/Important Bio-Agent (IBA)

24	CytokinesIBA 01/2022 - 05/2008
16	AntioxidantsIBA 02/2021 - 02/2005
15	Interleukin-17 (Interleukin 17)IBA 01/2022 - 05/2016
13	Transcription Factors (Transcription Factor)IBA 01/2022 - 09/2015
12	Imiquimod (Aldara)FDA LinkGeneric 01/2022 - 09/2015
12	Oxidants (Oxidizing Agents)IBA 02/2021 - 02/2005
10	3-nitrotyrosineIBA 10/2021 - 07/2015
10	Peroxidase (Myeloperoxidase)IBA 06/2020 - 09/2015
9	NADPH Oxidases (NAD(P)H oxidase)IBA 02/2021 - 08/2014
9	Lipid PeroxidesIBA 02/2021 - 02/2005
9	AllergensIBA 10/2019 - 03/2007
8	Proteins (Proteins, Gene)FDA Link 07/2020 - 02/2005
7	Chemokine ReceptorsIBA 01/2022 - 12/2016
5	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022 - 10/2016
5	Phosphotransferases (Kinase)IBA 01/2022 - 10/2019
5	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 01/2018 - 01/2017
5	Adenosine (Adenocard)FDA LinkGeneric 07/2010 - 12/2006
4	phthalic acid (phthalate)IBA 05/2022 - 12/2020
4	Interleukin-10 (Interleukin 10)IBA 01/2022 - 06/2020
4	Pharmaceutical PreparationsIBA 01/2022 - 07/2013
4	CreatinineIBA 10/2021 - 05/2017
4	Diethylhexyl Phthalate (DEHP)IBA 02/2021 - 01/2018
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2019
4	Biomarkers (Surrogate Marker)IBA 10/2020 - 08/2014
4	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2020 - 07/2015
4	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2017
4	Glutathione (Reduced Glutathione)IBA 01/2019 - 02/2005
4	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2016 - 08/2008
3	CopperIBA 01/2022 - 04/2016
3	Interleukin-9 (Interleukin 9)IBA 03/2021 - 10/2017
3	EnzymesIBA 02/2021 - 04/2016
3	Environmental Pollutants (Pollutants, Environmental)IBA 02/2021 - 08/2014
3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2021 - 10/2019
3	PlasticizersIBA 01/2021 - 01/2018
3	N- (1- (3- (4- ethoxyphenyl)- 4- oxo- 3,4- dihydropyrido(2,3- d)pyrimidin- 2- yl)ethyl)- N- pyridin- 3- ylmethyl- 2- (4- trifluoromethoxyphenyl)acetamideIBA 07/2020 - 12/2019
3	ibrutinibIBA 06/2020 - 10/2019
3	Tyrosine Kinase InhibitorsIBA 01/2020 - 10/2016
3	TyrphostinsIBA 01/2020 - 10/2016
3	AG 127 (AG 126)IBA 01/2020 - 10/2016
3	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2019 - 01/2018
3	Peptide Hydrolases (Proteases)FDA Link 05/2019 - 03/2011
3	NitrogenIBA 03/2019 - 05/2017
3	Urea (Carbamide)FDA LinkGeneric 03/2019 - 05/2017
3	Syk KinaseIBA 03/2019 - 03/2019
3	ResveratrolIBA 01/2018 - 12/2016
3	Purinergic P1 Receptors (Adenosine Receptor)IBA 07/2010 - 06/2007
2	OxidesIBA 01/2022 - 01/2022
2	CelluloseIBA 01/2022 - 01/2022
2	InterleukinsIBA 01/2022 - 12/2020
2	Biological ProductsIBA 01/2022 - 01/2022
2	Sulfhydryl Compounds (Thiols)IBA 01/2022 - 08/2014
2	Therapeutic UsesIBA 02/2021 - 10/2019
2	5-aminoisoquinolinoneIBA 02/2021 - 01/2020
2	Toll-Like Receptor 4IBA 07/2020 - 03/2017
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 07/2020 - 11/2015
2	GlucocorticoidsIBA 07/2020 - 11/2015
2	AntibodiesIBA 07/2020 - 01/2017
2	Immunoglobulin G (IgG)IBA 07/2020 - 03/2011
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 06/2020 - 01/2017
2	Dexamethasone (Maxidex)FDA LinkGeneric 10/2019 - 01/2018
2	sulforaphaneIBA 07/2019 - 01/2019
2	ChemokinesIBA 05/2019 - 11/2018
2	Triglycerides (Triacylglycerol)IBA 03/2019 - 01/2017
2	Acetates (Acetic Acid Esters)FDA Link 05/2018 - 01/2017
2	OvalbuminIBA 01/2018 - 03/2012
2	Interleukin-17 ReceptorsIBA 01/2018 - 01/2017
2	Dexrazoxane (Zinecard)FDA LinkGeneric 11/2017 - 01/2016
2	AnthracyclinesIBA 11/2017 - 01/2016
2	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2017 - 07/2015
2	STA-21IBA 01/2017 - 01/2017
2	LipopolysaccharidesIBA 01/2017 - 01/2015
2	IonomycinIBA 01/2017 - 01/2017
2	Dual OxidasesIBA 01/2017 - 07/2015
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2017 - 12/2014
2	phorbol-12-myristateIBA 01/2017 - 01/2017

Therapy/Procedure

13	Therapeutics 01/2022 - 02/2012